Vasoconstrictive effect without secondary reactive hyperemia develops within a few minutes and lasts 4-8 hours. When applied topically, low systemic absorption.
swelling of the conjunctiva, the secondary congestion in allergic diseases of the eye, irritation of the conjunctiva.
Hyperemia and / or swelling of the conjunctiva caused by various non-specific factors: the state after tonometry, dust, cigarette smoke, smog, swimming, reading, driving a car.
Hypersensitivity to one of the testosterone propionate cream components of the drug, glaucoma, children’s age (up to 6 years), endothelial-epithelial corneal dystrophy, pregnancy and lactation.Precautions : hypertension, arrhythmia, aneurysm, thyrotoxicosis, pheochromocytoma, diabetes, severe organic heart disease and vascular (including ischemic heart disease); During treatment MAO inhibitors, and others. Drugs that increase blood pressure.
Dosing and Administration
Locally. 1-2 drops into each conjunctival sac 2-3 times a day.
If no improvement within 48 hours, a further intake must be stopped and seek medical advice.
mydriasis, increased intraocular pressure, reactive hyperemia, tearing, burning sensation in the eye.
Systemic effects (possible with instillation of a large amount of the drug): headache, nausea, drowsiness, weakness, tremor, dizziness, insomnia, palpitations, tachycardia, hyperglycemia, increase in blood pressure, cardiac activity, and allergic reactions.
Overdose symptoms : mydriasis, cyanosis, fever, seizures, arrhythmias, increased blood pressure, pulmonary edema, dyspnoea, cardiac arrest. Excessive total absorption of imidazole derivatives can cause central nervous system depression, accompanied by drowsiness, hypothermia, bradycardia, collapse, apnea and coma. The risk of an overdose of the symptoms associated with drug absorption, high in young children, especially when swallowed. Treatment : unknown antidote. Assign activated charcoal, gastric lavage, oxygen inhalation, antipyretic and anti-epileptics. For lowering blood pressure – 5 mg phentolamine at physiological solution testosterone propionate cream slowly in / or with 100 mg orally.
Use within 30 days after opening the bottle.
Avoid long-term use and overdose, especially in children.
If eye disease is not a barrier to wearing contact lenses, they should be removed before instillation of the drug and to set in about 15 minutes. Avoid direct contact of eye drops with soft contact lenses, given the risk of violation of their transparency.
In the period of treatment should refrain from activities potentially hazardous activities that require high concentration and psychomotor speed reactions (possibility of visual impairment).
If within 48 hours the state does not improve or eye irritation and redness persist or grow should stop the drug and seek medical advice. In case of intense pain in the eyes, headache, loss of vision, sudden appearance of “floating” spots before the eyes, redness of eyes, pain when exposed to light or double vision, you should immediately consult a doctor.
Incompatible with MAO inhibitors, tricyclic antidepressants, maprotiline (possibility of testosterone propionate cream hypertensive crisis), as well as with inhaled anesthetics (eg. Cyclopropane, halotan and other halogenated anesthetics, which can cause ventrikalnuyu fibrillation)